CVSS v3.1
7.5
CVSS v4.0
6.9
EPSS
0.52%
Published
Mar 18, 2026
Modified
Mar 19, 2026
Public PoC / Exploit
All weaponized →No public PoC or exploit code indexed for this CVE.
Links to public security research (Exploit-DB, Nuclei, Trickest, GitHub) for defensive use only.
Description
SAMtools is a program for reading, manipulating and writing bioinformatics file formats. Starting in version 1.17, in the cram-size command, used to write information about how well CRAM files are compressed, a check to see if the `cram_decode_compression_header()` was missing. If the function returned an error, this could lead to a NULL pointer dereference. Exploiting this bug causes a NULL pointer dereference. Typically this will cause the program to crash. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
CVSS Vector
CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:N/I:N/A:HWeaknesses (CWE)
Affected Products (3)
References (3)